Urticaria, more commonly known as hives, is a prevalent inflammatory skin condition appearing as pink to red raised welts on the skin. Key symptoms include intense itching, localized swelling, and irritation, with swelling often occurring around sensitive areas like the eyes or lips. In severe instances, urticaria can cause airway or throat swelling, posing a risk to breathing. This skin reaction usually results from an overactive immune response, which may be triggered by an allergy or an underlying imbalance taking place within the body.
Hives, also called urticaria, is an inflammatory skin condition characterized by pink or red raised welts on the skin. Swelling can often accompany these welts, particularly around sensitive areas such as the eyes or lips. In severe cases, hives can lead to airway or throat swelling, also known as anaphylaxis, which demands immediate emergency care. This condition arises from an overactive immune response, where certain immune cells release histamine and other chemicals. While hives may be triggered by an allergic reaction or external irritants, the exact cause often remains unclear.
Hives are categorized based on how long they last: “acute urticaria” and “chronic urticaria.” Acute urticaria usually clears up within six weeks and is often tied to specific allergies, ranging from foods and certain medications to infections or environmental factors. In contrast, chronic urticaria persists beyond six weeks and is idiopathic, i.e., has an unknown origin. This prolonged form of hives can present treatment challenges due to its stubborn nature and unclear cause.
The potential triggers for hives are numerous, which can make pinpointing the exact cause challenging. In fact, over half of all cases have no identifiable cause. However, there are specific subtypes of chronic hives, collectively known as chronic inducible urticaria, each with its own distinct triggers:
The primary goal of treating hives is to relieve itching and help prevent relapses. Keeping a journal to track potential triggers can be useful in identifying the specific cause. If any are discovered, avoidance becomes essential.
For medical management, oral antihistamines are typically the first line of treatment. Common over-the-counter, non-drowsy options include loratadine (Claritin), cetirizine (Zyrtec), and fexofenadine (Allegra), while the sedating option diphenhydramine (Benadryl) can be used as needed. Prescription antihistamines, such as hydroxyzine (Atarax) and desloratadine (Clarinex), are also available for more persistent cases.
Topical anti-itch creams offer temporary relief and may contain ingredients like pramoxine, calamine, or menthol. In certain cases, topical steroid creams, lotions, or ointments can be prescribed, and oral steroids may be recommended briefly for severe outbreaks.
Treating chronic urticaria is often complex and may require different strategies. When antihistamines and topical treatments are not effective, immunosuppressant therapies may be considered under the supervision of an allergist to help reduce the heightened immune response.
It’s essential to seek emergency care immediately if hives are accompanied by symptoms like swelling around the lips or mouth, difficulty swallowing or breathing, dizziness, or a rapid heartbeat. These can signal a serious reaction needing urgent treatment.